Aim and Objective- The most distressing symptoms that follow anaesthesia and surgery are pain and vomiting. The aim of this study is to compare the antiemetic efficacy of Granisetron against that of Ondansetron by comparing the incidence of PONV using each drug. Methods: prospective randomized single blinded control study the patients were randomly divided into three groups of 30 patients each.
Group A: Normal Saline, Group B: Ondansetron (0.08mg/kg), Group C:Granisetron (0.04mg/kg) Discussion: PONV are observed after general, regional and local anaesthesia. Several factors such as patient factors like age, gender, obesity, anxiety, history of motion sickness, vomiting and gastro paresis; type of surgery .
The surgical technique is highly standardized, therefore the choice of anaesthetic technique is the main variable available to influence PONV Conclusions: Patients who received Granisetron and Ondansetron had significantly less PONV compared to the group that received normal saline; and with Granisetron the incidence was significantly lower than that with Ondansetron.