To compare onset and duration of sensory and motor blockade and intra-operative haemodynamic changes in the following 3 groups: 1. Hyperbaric Bupivacaine 0.5% and Fentanyl 25 micro grams 2. Hyperbaric Bupivacaine 0.5% and Clonidine 30 micro grams 3. Hyperbaric Bupivacaine 0.5% and Dexmedetomidine 5 micro grams when given intrathecally.

90 patients undergoing elective procedures under spinal anesthesia for lower abdominal surgeries at Government General Hospital, Vijayawada were included for the study. Inclusion Criteria: 1. Patients of either sex. 2. Patients with ASA Grade-I and Grade-II 3. Patients aged between 20-50 years.

1. The onset of sensory blockade did not vary significantly between the groups. 2. The onset of motor blockade was earlier in Dexmedetomidine group when compared to Fentanyl and Clonidine groups. 3. Duration of sensory and motor blockade was prolonged in Dexmedetomidine, when compared to Fentanyl and Clonidine, which were both comparable. 4. The haemodynamic parameters did not vary significantly between the 3 groups. To summarize, intrathecaldexmedetomidine provides better quality and longer duration of motor and sensory blockade, longer duration of analgesia with minimum side effects.

1. Addition of Fentanyl, Clonidine or Dexmedetomidine to intrathecal Bupivacaine will prolong the duration of sensory and motor blockade. 2. Supplementation of intrathecal bupivacaine with either fentanyl, clonidine or with dexmedetomidine increases the duration of postoperative analgesia. 3. There are no significant side effects by adding Fentanyl, Clonidine /Dexmedetomidine