Abstracts / Free Papers

Comparision of effects of dexmedetomidine infusion Vs propofol infusion during air oxygen based anaesthesia in patients undergoing robotic assisted laparoscopic pelvic surgeries.

Dr Tejinder Singh Jaggi

Department : Anesthesiology Rajiv Gandhi Cancer Institute & Research Center

Dr. Tejinder Singh jaggi, Dr. Itee Chowdhury, Dr. Shagun Bhatia Shah, Dr.Col.AK Bhargava

ABSTRACT : 1-To compare hemodynamics in both groups. 2-To compare time to reach BIS value standards of 80 at the end of anaesthesia. 3-To compare total dose of analgesic perioperatively in the form of fentanyl used in both the groups. 4-To study and compare early recovery characteristics and Modified Aldrete recovery score in both the groups.

METHODS : 80 ASA physical status I- II patients, 30 -65 years, BMI ≤30 undergoing surgery for 120-180 minutes. Computer randomisation, 40 each, in dexmedetomidine group D and in propofol group P. Induction with fentanyl 1.5 mcgmkg-1 and propofol 2mgkg-1. Maintained with desflurane 3-5% with air 50% and O2 50%. In D group ( bolus 0.5 mcgmkg-1 for 10 minutes then maintenance 0.2-0.5 mcgmkg-1hr-1) and in P group ( propofol @ 50-150 mcgkg-1min-1) started. At docking of robotic arms single dose morphine @ 0.075 mgkg-1 in both groups is given. Hemodynamic stability (MAP and HR) is adjusted within 20% of base line values.

RESULTS : Early and intermediate recovery,total fentanyl requirement intraoperatively and post operatively were less in D group

CONCLUSIONS : Dexmedetomidine more effective for both intraoperative and postoperative analgesia. Recoveries both early and intermediate are faster in dexmedetomidine group