Abstracts / Free Papers
Accidental Dopamine Toxicity- A Case Report
Institute : AgartalaGovt Medical College
Authors : 1.Dr BiswajitSutradhar, 2.Dr S B Chakraborty, 3.Dr MonotoshPramanik, 4.Dr JoydeepDebnath
ABSTRACT : Introduction
Dopamine is an ionotrop agent used to treat hypotension, shock & usually kept in emergency kit. Accidental administration of dopamine is very rare as it is used by health professionals but it can occur as in this case.
METHODS : Case overview
A 42 years female patient of ASA I with fibroid uterus was posted for total abdominal hysterectomy. During premedication accidentally iv dopamine was administered to her. Immediately the patient suffered from restlessness, palpitation, chest tightness, tachycardia, hypertension, excessive salivation, nausea & vomiting. The drug error was immediately detected. The patient was successfully managed with inj furosemide, injesmolol, injglycopyrrolate, injondansetron, iv fluid & 100% oxygen in the OT. Spo2, HR, NIBP, ECG & urine output were monitored. The case was followed up, surgery deferred but performed later on successfully.
RESULTS : Discussion
Dopamine toxicity among the chronic users are common but inadvertent dopamine injection is very rare. Acute dopamine toxicity needs emergency care. Phentolaminean α blocker, is the antidote to dopamine but in the absence of phentolamine aggravated diuresis with furosemide & maintenance of hemodynamic stability with appropriate agents can save the life of patient.
CONCLUSIONS : Conclusion
Dopamine ampule should be kept away from similar kind of ampules preferably in emergency kit. Drug error should be timely detected & managed with emergency care to prevent fatal consequence.